Leptospermum scoparium, commonly called mānuka, manuka, manuka myrtle, New Zealand teatree, broom tea-tree, or just tea tree, is a species of flowering plant in the myrtle family Myrtaceae, native to south-east Australia and New Zealand (including the Chatham Islands).

It is a prolific scrub-type tree and is often one of the first species to regenerate on cleared land. It is typically a shrub growing to 2–5 m (7–16 ft) tall, but can grow into a moderately sized tree, up to 15 m (49 ft) or so in height. ...

leptospermum scoparium

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The-Natural-Allies:-Garlic-and-Honey

The Natural Allies: Garlic and Honey

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Garlic, or Allium sativum, is a species in the onion genus, Allium. Beloved for its pungent taste, it enhances a plethora of dishes worldwide. Apart from its culinary significance, garlic's medicinal properties have been recognized for centuries, from the ancient Egyptians to traditional Chinese and Ayurvedic medicine.

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Garlic owes its medicinal prowess to the sulfur compounds formed when a clove is chopped, crushed, or chewed. These compounds include allicin, a potent bioactive compound with broad-spectrum antimicrobial activity.

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Honey, on the other hand, is the sweet nectar produced by bees from the flowers they pollinate. The type of honey often depends on the source of the nectar, for instance, Manuka honey originates from the nectar of the Manuka tree (Leptospermum scoparium).

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Honey's antibacterial properties primarily stem from its acidic pH and the presence of hydrogen peroxide, generated by the enzymatic activity of bees. It's also rich in polyphenols and flavonoids, which have antioxidant and anti-inflammatory properties.

Photo by bruno neurath-wilson on Unsplash

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The-Battle-Against-E.-coli

The Battle Against E. coli

The-Battle-Against-E.-coli_1_0

Escherichia coli, or E. coli, is a bacterium that is commonly found in the gut of warm-blooded organisms. Most strains are harmless and even beneficial, but some can cause severe infections. Both garlic and honey have demonstrated efficacy against E. coli.

The-Battle-Against-E.-coli_1_1

Garlic's antimicrobial compounds disrupt the bacteria's cell membrane, inhibit its enzyme activity, and interfere with its DNA, effectively limiting its growth and spread. Similarly, honey creates a hostile environment for E. coli through its acidity, osmotic effect, and the antimicrobial compounds it contains.

Recipes:-Incorporating-Garlic-and-Honey

Recipes: Incorporating Garlic and Honey

Garlic-Infused-Honey

Garlic Infused Honey

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<ul><li style="font-weight: 400;" aria-level="1">1 cup of honey (preferably raw and organic)</li><li style="font-weight: 400;" aria-level="1">10-12 cloves of garlic</li></ul>Instructions:

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<ol><li style="font-weight: 400;" aria-level="1">Peel and lightly crush the garlic cloves.</li><li style="font-weight: 400;" aria-level="1">Place the garlic in a clean, dry jar.</li><li style="font-weight: 400;" aria-level="1">Pour honey over the garlic and ensure all cloves are covered.</li><li style="font-weight: 400;" aria-level="1">Close the jar and let it sit for 3-4 days, stirring once daily.</li><li style="font-weight: 400;" aria-level="1">The garlic-infused honey can be taken on an empty stomach, one spoonful a day.</li></ol>

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Garlic-Honey-Tea

Garlic-Honey Tea

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Garlic-Honey-Tea_2_1

<ul><li style="font-weight: 400;" aria-level="1">1 cup of water</li><li style="font-weight: 400;" aria-level="1">1-2 cloves of garlic</li><li style="font-weight: 400;" aria-level="1">1 tablespoon of honey</li></ul>Instructions:

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<ol><li style="font-weight: 400;" aria-level="1">Crush the garlic cloves and let them sit for a few minutes.</li><li style="font-weight: 400;" aria-level="1">Boil a cup of water.</li><li style="font-weight: 400;" aria-level="1">Add the crushed garlic to the boiling water and let it steep for 10 minutes.</li><li style="font-weight: 400;" aria-level="1">Strain the tea and stir in a tablespoon of honey.</li><li style="font-weight: 400;" aria-level="1">Drink this tea once or twice a day.</li></ol>

Garlic,-Honey-and-their-Anticancer-Properties

Garlic, Honey and their Anticancer Properties

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In addition to battling E.coli, both garlic and honey have been suggested to possess anticancer properties. In garlic, organosulfur compounds have shown potential in inhibiting cancer growth and proliferation<a href="https://chat.openai.com/#user-content-fn-7%5E" target="_blank" rel="noopener">7</a>. Meanwhile, honey, particularly Manuka honey, has shown promise in inducing apoptosis (cell death) in cancer cells.

Questions-and-Answers

Questions and Answers

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Q: Can I use any type of honey for the recipes?

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A: It's best to use raw, organic honey as it retains most of its medicinal properties which could be lost in highly processed varieties.

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Q: Can I consume garlic and honey while on antibiotics?

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A: &nbsp;While generally safe, it's always best to consult with your healthcare provider, as certain combinations can affect the absorption or efficacy of your medicine.

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Q: Can garlic and honey cure an E. coli infection?

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A: &nbsp;Garlic and honey can inhibit E. coli, but they're not a substitute for medical treatment. If you suspect an E. coli infection, seek professional medical advice.

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Q: How often can I consume these remedies?

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A: &nbsp;Generally, one to two servings a day should be fine. But if you have any underlying health conditions, consult your doctor first.

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Q: Can children consume these garlic and honey remedies?

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A: &nbsp;While generally safe for children, honey should not be given to infants under one year of age due to the risk of botulism.

References

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<ul><li style="font-weight: 400;" aria-level="1"><a href="https://pubmed.ncbi.nlm.nih.gov/25050296/" target="_blank" rel="noopener">Garlic: a review of potential therapeutic effects</a><a href="https://chat.openai.com/#user-content-fnref-1%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609166/" target="_blank" rel="noopener">Honey: its medicinal property and antibacterial activity</a><a href="https://chat.openai.com/#user-content-fnref-2%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://pubmed.ncbi.nlm.nih.gov/22280901/" target="_blank" rel="noopener">Antibacterial effect of garlic (Allium sativum) on Staphylococcus aureus: an in vitro study</a><a href="https://chat.openai.com/#user-content-fnref-3%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://pubmed.ncbi.nlm.nih.gov/10879424/" target="_blank" rel="noopener">Antibacterial activity of honey against strains of Staphylococcus aureus from infected wounds</a><a href="https://chat.openai.com/#user-content-fnref-4%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://pubmed.ncbi.nlm.nih.gov/10594976/" target="_blank" rel="noopener">Antimicrobial properties of allicin from garlic</a><a href="https://chat.openai.com/#user-content-fnref-5%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424551/" target="_blank" rel="noopener">Honey and Health: A Review of Recent Clinical Research</a><a href="https://chat.openai.com/#user-content-fnref-6%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://pubmed.ncbi.nlm.nih.gov/31897129/" target="_blank" rel="noopener">Organosulfur Compounds and Cancer</a><a href="https://chat.openai.com/#user-content-fnref-7%5E" target="_blank" rel="noopener"> </a></li><li style="font-weight: 400;" aria-level="1"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822819/" target="_blank" rel="noopener">The potential role of honey and its polyphenols in preventing heart disease: A review</a><a href="https://chat.openai.com/#user-content-fnref-8%5E" target="_blank" rel="noopener"> </a></li></ul>

Garlic and honey are powerful natural remedies that have been used for centuries. Their antimicrobial properties, including against E. coli, can be attributed to a range of bioactive compounds such as allicin in garlic and hydrogen peroxide in honey. Incorporating these natural remedies in your diet can be as simple as making garlic-infused honey or a comforting garlic-honey tea. Beyond their antibacterial qualities, these substances also show promising anticancer properties.

Battling E.coli Infections: The Role of Garlic and Honey

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Natural-Remedies-to-Fight-Escherichia-coli

Natural Remedies to Fight Escherichia coli

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Deriving their power from various plants revered for their robust antibacterial properties, these herbal mixtures offer an alternative approach to battling E.coli. Let's explore some recipes you can prepare at home.

Garlic-(Allium-sativum)-and-Honey-(Apis-mellifera)-Mixture:-The-Potent-Natural-Duo

1. Garlic (Allium sativum) and Honey (Apis mellifera) Mixture: The Potent Natural Duo

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Garlic, a staple in kitchens globally, is also a star player in the medicinal field. Its primary active compound, allicin, is renowned for its robust antibacterial, antiviral, and anti-fungal properties. Furthermore, garlic promotes cardiovascular health and battles oxidative stress with its antioxidant arsenal.

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Manuka honey, a unique produce of New Zealand bees, teams up with garlic to unleash potent antibacterial qualities. It's acclaimed for promoting wound healing and mitigating symptoms of chronic conditions like Irritable Bowel Syndrome (IBS) and gastric ulcers.

Recipe

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<ul><li>3 cloves of garlic</li><li>1 tablespoon of Manuka honey</li></ul>Instructions:

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<ul><li>Crush the garlic cloves and let them sit for 15 minutes to allow the compound allicin to form.</li><li>Mix the crushed garlic with the honey.</li><li>Consume this mixture once a day.</li></ul>

Recipe_0_3

Echinacea-(Echinacea-purpurea)-and-Golden-Seal-(Hydrastis-canadensis)-Tea:-The-Immune-System's-Allies

2. Echinacea (Echinacea purpurea) and Golden Seal (Hydrastis canadensis) Tea: The Immune System's Allies

Echinacea-(Echinacea-purpurea)-and-Golden-Seal-(Hydrastis-canadensis)-Tea:-The-Immune-System's-Allies_0_0

Echinacea, a group of flowering plants commonly used in traditional medicine, touts immune-boosting properties, known to reduce symptoms of common colds and flu. It also hosts phenols, compounds with potent antioxidant properties.

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Golden Seal, a herb native to North America, is widely used for mucous membrane infections. It's also known to reduce inflammation and battle bacterial and fungal infections. Some advocate its use for digestive issues.

<ul><li>1 teaspoon of Echinacea root</li><li>1 teaspoon of Golden Seal root</li><li>2 cups of water</li></ul>Instructions:

<ul><li>Combine both roots with water in a pot.</li><li>Boil the mixture for about 15-20 minutes.</li><li>Strain and drink the tea twice a day.</li></ul>

Turmeric-(Curcuma-longa)-and-Black-Pepper-(Piper-nigrum)-Drink:-The-Golden-Inflammation-Fighters

3. Turmeric (Curcuma longa) and Black Pepper (Piper nigrum) Drink: The Golden Inflammation Fighters

Turmeric-(Curcuma-longa)-and-Black-Pepper-(Piper-nigrum)-Drink:-The-Golden-Inflammation-Fighters_0_0

Turmeric, a golden spice common in traditional medicine and Asian cuisine, is a storehouse of curcumin. This compound is applauded for its powerful anti-inflammatory and antioxidant properties, and has been linked to improved brain function and a lower risk of chronic diseases.

Turmeric-(Curcuma-longa)-and-Black-Pepper-(Piper-nigrum)-Drink:-The-Golden-Inflammation-Fighters_0_1

Black pepper enhances nutrient absorption, particularly curcumin. Moreover, it showcases anti-inflammatory properties and may promote digestion and intestinal health.

<ul><li>1 teaspoon of turmeric powder</li><li>1/2 teaspoon of ground black pepper</li><li>1 cup of water</li></ul>Instructions:

<ul><li>Add turmeric and black pepper to the water.</li><li>Bring the mixture to a boil and let it simmer for 10 minutes.</li><li>Drink this mixture once or twice a day.</li></ul>Remember, these herbal mixtures serve as a supplement and should not replace a proper medical treatment plan. Always consult with your healthcare provider before starting any new regimen. The journey of unraveling herbal medicine's potentials reminds us that these remedies' effectiveness may vary between individuals. Yet, their benefits extend beyond battling bacteria, contributing to a holistic and healthier lifestyle.

Harness the potential of these herbs and explore their myriad health benefits. Remember, moderation is key in their consumption, and they should not substitute for medical treatment. Always consult with a healthcare provider before starting any new herbal regimen.

Refencies

Refencies_1_0

<ol><li>Garlic's Antimicrobial potential</li><li>Manuka honey's antibacterial properties</li><li>Echinacea &amp; Golden Seal's immune-boosting effects</li><li>Curcumin's antibacterial activity</li><li>Piperine's enhancement of curcumin absorption</li></ol>

In conclusion, while E.coli infections can pose serious health risks, nature provides us with a plethora of potential remedies. Whether it's garlic's potent allicin or the immune-boosting power of Echinacea, these natural treatments offer promising alternatives. By harnessing the power of these herbal mixtures, we can tap into their many benefits, promoting not just the fight against E.coli, but a holistic approach to a healthier life.

Natural Remedies for E.coli Infections: Harnessing the Power of Herbal Mixtures

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Natural Remedies for E.coli Infections: Harnessing the Power of Herbal

Author: Sylvia Marinova, PhD student in in the "Genomic Stability" lab at BAS

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Helicobacter pylori is a type of bacterium that colonizes the gastrointestinal tract.&nbsp;It is the most common cause of stomach and duodenal ulcers and gastritis. In addition, infected people are associated with a 2 to 6-fold increased risk of developing stomach cancer <a href="https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-infectious-diseases/helicobacter-pylori" target="_blank" rel="noopener">[ref.1]</a>. The infection is often asymptomatic, but can often cause some of the following symptoms:

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<ul>
<li style="font-weight: 400;" aria-level="1">burning in the stomach and esophagus</li>
<li style="font-weight: 400;" aria-level="1">stomach pain</li>
<li style="font-weight: 400;" aria-level="1">vertigo</li>
<li style="font-weight: 400;" aria-level="1">swelling</li>
<li style="font-weight: 400;" aria-level="1">unexplained weight loss</li>
<li style="font-weight: 400;" aria-level="1">loss of appetite, etc.</li>
</ul>

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It is believed that over 50% of the global population is infected with H.pylori <a href="https://pubmed.ncbi.nlm.nih.gov/23165522/" target="_blank" rel="noopener">[ref.2]</a> and the problem is greatest in developed countries.&nbsp;In this article we will look at conventional treatment, its disadvantages and why it is necessary to look for alternative natural solutions to deal with the bacterium.

Standard-therapy

Standard therapy

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The most desirable outcome in the treatment of this infection is complete clearance of the bacteria. This is because H.pylori can stay in the stomach for an extremely long time and lead to chronic diseases such as gastritis, ulcers or cancer. Medical practice recommends therapies with acidity regulators, such as proton pump inhibitors, and antibiotics <a href="https://www.sciencedirect.com/science/article/abs/pii/S1521691806001387?via%3Dihub" target="_blank" rel="noopener">[ref.3]</a>.

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Unfortunately, often the treatment is not successful for two main reasons - the increasing antibiotic resistance of the bacterium and non-compliance with the course of treatment by patients. Usually, therapy involves at least three drugs and lasts&nbsp; for a long time, and the results do not always come immediately. On the other, the appearance of side effects and the high cost of treatment act discouragingly, and patients give up treatment before a complete cure.

Virulent-factors-of-H.pylori

Virulent factors of   H.pylori

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Various products of microorganisms that help them cause an infectious process in the host are indicated as virulence factors. Examples include some toxins, receptors on the surface, etc. In the case of H.pylori, it is about factors that help it colonize the stomach and survive in the highly acidic environment there.

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Among them are urease and adhesins. Urease is an enzyme with which the bacterium neutralizes gastric acid by converting urea into ammonia and carbon dioxide <a href="https://www.bioseek.eu/bg/bul/research/pubmed/The_role_of_Helicobacter_pylori_urease_in_the_pathogenesis_of_gastritis_and_peptic_ulceration_8730260" target="_blank" rel="noopener">[ref.4]</a>. In addition, there are non-invasive tests that use the reaction of this enzyme to determine the presence of helicobacter and diagnosis, as well as to monitor the effect of assigned treatment.&nbsp;&nbsp;

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Adhesins, on the other hand, are necessary for the bacterium to capture it for the epithelial cells of the stomach. They help it to resist adverse environmental conditions such as the constant flow of juices and peristaltic movements <a href="https://www.bioseek.eu/bg/bul/research/pubmed/Adhesion_and_Invasion_of_Gastric_Mucosa_Epithelial_Cells_by_Helicobacter_pylori_27921009" target="_blank" rel="noopener">[ref.5]</a>.

Plants-as-an-alternative-treatment

Plants as an alternative treatment

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Traditional medicine should not be neglected when we talk about infection with H.pylori. Many studies can be found in scientific databases that study the antibiotic effects of various plants on this bacterium.&nbsp;In addition to individual species, some studies also focus on isolating individual pure compounds with this effect, as well as on their chemical modification to create new medicines.

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When reading such literature, however, it should be taken into account that in vitro studies are often carried out, i.e. in a test tube. This is a good start, but it is also necessary to have in vitro data in order to make the action more secure. In the examples of plants with healing effect on H.pylori we will see mainly those whose effect is also studied on model organisms.

How-medical-plants-could-counteract-H.pylori

How medical plants could counteract  H.pylori  

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Many natural plant products have anti-H.pylori action. Some of the mechanisms of action against the bacterium include suppression of the activity of urease, damage to genetic material, suppression of protein synthesis and virulent factors, activity againt adhesins, etc.

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For example, a 2005 study showed that aqueous extracts of borage, turmeric and parsley prevented the capture of H. pylori for gastric epithelial cells <a href="https://www.bioseek.eu/bg/bul/research/pubmed/Bactericidal_and_anti_adhesive_properties_of_culinary_and_medicinal_plants_against_Helicobacter_pylori_16437723" target="_blank" rel="noopener">[ref.6]</a>. A similar effect was found in the aqueous extract of the well-known herb licorice <a href="https://www.bioseek.eu/bg/bul/research/pubmed/Aqueous_extracts_and_polysaccharides_from_liquorice_roots_Glycyrrhiza_glabra_L_inhibit_adhesion_of_Helicobacter_pylori_to_human_gastric_mucosa_19607905" target="_blank" rel="noopener">[ref.7]</a>.

5-natural-remedies-against-H.pylori

5 natural remedies against  H.pylori  

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The ingredient of red wine, to which its effects are due, is resveratrol. It is a natural antioxidant that has shown activity against the urease of H.pylori, as well as against <a href="https://www.sciencedirect.com/science/article/pii/S0963996911001049?casa_token=zFNTOThBYU4AAAAA:-qyU52IVRuOBqN2-tBgM8rkaBajprHOVCn5bRZ4ynHQ3HxKnsSzqXGrs-vuJD8TAWT61zGjkgw" target="_blank" rel="noopener"> [ref.8]</a>.

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Broccoli

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Isothiocyanate sulforaphane is the metabolized product of substances, which are abundantly found broccoli, especially in their sprouts, and has bacteriostatic action against H.pylori and other bacteria.

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Read more in <a href="../p/dobritie_i_loshitie_taini_na_brokolitie" target="_blank" rel="noopener">The Good and The Bad Secrets of Broccoli</a>

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A 2011 study showed that that the intake of broccoli sprouts reduces the colonization of the gastric mucosa by the bacterium, reduces inflammation and oxidative stress in mouse models and in humans <a href="https://www.bioseek.eu/bg/bul/research/pubmed/Sulforaphane_enhances_protection_and_repair_of_gastric_mucosa_against_oxidative_stress_in_vitro_and_demonstrates_anti_inflammatory_effects_on_Helicobacter_pylori_infected_gastric_mucosae_in_mice_and_human_subjects_21548875" target="_blank" rel="noopener">[ref.9]</a>. 48 volunteers took 70 g of broccoli sproutsfor 8 weeks. 2 months after stopping sprout intake, however, it was found that the indicators returned to the original values. This indicates that broccoli has an effect on the suppression of the bacterium, but can not completely eradicate it.&nbsp;

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The catechins in green tea are the main antioxidant in this plant. They have shown antibiotic action against H.pylori. In addition, a study on model animals shows that intake of green tea extract for 6 weeks significantly reduces the symptoms of gastritis, as well as the number of bacteria <a href="https://www.bioseek.eu/bg/bul/research/pubmed/Suppression_of_Helicobacter_pylori_induced_gastritis_by_green_tea_extract_in_Mongolian_gerbils_14550260" target="_blank" rel="noopener"> [ref.10]</a>.

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Probiotics are live bacteria that help maintain the balance of microflora in the digestive tract. Fermented foods and drinks such as yogurt, kimchi, kefir, kombucha, etc. are natural sources of probiotic bacteria, while today many ready-made dietary supplements can also be found.

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Their use as a complementary or alternative treatment for H.pylori infection is mentioned more and more in the medical literature.&nbsp;Probiotics are known to have an in vitro suppressive effect against this bacterium and also to reduce the symptoms associated with inflammation in gastritis in vivo. For example, the authors of a summary article from 2014 show that of the 12 articles studying the treatment of H. pylori with antibiotics combined with probiotics and 16 studying probiotics as the only treatment, most reported an improvement in patient complaints and a reduction in the number of pathogenic bacteria. However, none showed a complete cure from the infection with probiotics alone <a href="https://www.sciencedirect.com/science/article/pii/S1684118213000637?via%3Dihub" target="_blank" rel="noopener">[ref.11]</a>.

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Honey and propolis

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Honey is well <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925854/?fbclid=IwAR1pFDbib3yg1j_9dwj8H46FH0g1mM9Ikup8BfA3K31u2kaxo_NtwOg_0sY" target="_blank" rel="noopener"></a>known for its antibacterial properties and has several possible mechanisms that explain its action.&nbsp;There are also studies that examine its depressant effect specifically on H.pylori, as manuka honey seems to give the most promising results <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925854/?fbclid=IwAR1pFDbib3yg1j_9dwj8H46FH0g1mM9Ikup8BfA3K31u2kaxo_NtwOg_0sY" target="_blank" rel="noopener">[ref.12]</a>.

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In conclusion, alternative treatments for H. pylori are a good approach and are probably safe. However, they have not been shown to completely cure infections with this bacterium and are rather recommended as concomitant treatment with a preparation after consultation with your doctor.

Natural Treatments for Helicobacter pylori

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 Natural Treatments for Helicobacter pylori

Силвия Маринова

Author: Yana Nencheva, Biochemist, PhD candidate in Biophysics

When it rains and you freeze, you rush home, eat a spoonful of honey and take a hot shower to стоп the cold. But honey can be used on at least 7 different occasions.

The sweet liquid produced by the honey bee is recognized ubiquitously for its beneficial effect on the body. Since ancient times in India, lotus honey has been used to treat eye infections. Since then, Egyptians, Greeks and Chinese have used it to treat intestinal diseases (incl. stomach ulcers). Today it is a means of increasing immunity, treatment for cough, sore throat, ears and much more.

What-does-honey-contain?

What does honey contain?

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Honey is the only food that does not have a shelf life, but what does it contain? Generally speaking natural honey consists of at least 181 ingredients. Honey is an oversaturated sugar solution, including:

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<ul>
<li dir="ltr">
80% carbohydrates - 38% fructose, 30% glucose, 12% other sugars,
</li>
<li dir="ltr">
17% water,
</li>
<li dir="ltr">
0,5 % protein, enzymes, organic acids, minerals, amino acids, vitamins, phenols, aromatic compounds, polyphons and other components,
</li>
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small amounts of bioactive components - phenolic acid, flavonoid α-tocopherol.
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</ul>

What-does-honey-contain?_0_2

Honey is known for its <a href="/p/kakvi_sa_polzitie_ot_antioksidantitie_za_zdravieto_i_koi_khrani_sa_nai_boghati_na_tiakh_0376155d_ea0c_4218_8ed2_114aed9f37c5" target="_blank" rel="noreferrer">antioxidant activity</a>. For this, when scientists study it, they measure the content of ascorbic acid and the different enzymes in it (such as catalase (CAT), glutathione peroxidase (GPO), superoxide dismutase (SOD)) [ref. 1].

leptospermum scoparium

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