A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis&nbsp;&nbsp;

Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors, Science Advances 27 Aug 2021&nbsp;

Targeting hypoxia in cancer therapy. Nat Rev Cancer. 2011 Jun;11(6):393-410. doi: 10.1038/nrc3064. PMID: 21606941.

Ferroptosis in Cancer Treatment: Another Way to Rome Front. Oncol., 25 September 2020&nbsp;

Kojin bags $60M to exploit weakness of drug-resistant cancers&nbsp;

Lung cancer patients in England to receive ‘breakthrough’ tumour-stopping drug&nbsp;

Ракът е коварно и тежко заболяване, което сломява не само тялото, но и човешкия дух. Когато е злокачествен (в много редки случаи и доброкачествените тумори са животозастрашаващи), това може да означава дълги години борба и опити за оцеляване. Новите имунологични терапии на ракови заболявания дават надежда за по-добър изход, години преживяемост и успешна възстановителна терапия. Знайте, че ракът спада към групата на лечимите заболявания и всяка стъпка в процеса на диагностика и лечение е решаваща за благоприятно развитие. Нашият екип ще ви държи в течение за най-новите открития и постижения в областта, както винаги в портала <a href="../../" target="_blank" rel="noopener">Sanat.io</a>.

Светлина в тунела - раковите тумори и тяхната “ахилесова пета”

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 Светлина в тунела - раковите тумори и тяхната “ахилесова пета”

Бетина Цветкова

Dimitriadis, E., Menkhorst, E., Saito, S.&nbsp;et al. (2020).&nbsp;Recurrent pregnancy loss.&nbsp;Nature Reviews Disease Primers6,&nbsp; <a href="https://doi.org/10.1038/s41572-020-00228-z" target="_blank" rel="noopener">https://doi.org/10.1038/s41572-020-00228-z</a>

Pal, A. K., et al. (2018). Chromosomal Aberrations in Couples with Pregnancy Loss: A Retrospective Study.&nbsp;Journal of human reproductive sciences,&nbsp;11(3), 247–253. <a href="https://doi.org/10.4103/jhrs.JHRS_124_17" target="_blank" rel="noopener">https://doi.org/10.4103/jhrs.JHRS_124_17</a>

Hyde, K. J., &amp; Schust, D. J. (2015). Genetic considerations in recurrent pregnancy loss.&nbsp;Cold Spring Harbor perspectives in medicine,&nbsp;5(3), a023119. <a href="https://doi.org/10.1101/cshperspect.a023119" target="_blank" rel="noopener">https://doi.org/10.1101/cshperspect.a023119</a>

El Hachem, H., et al. (2017). Recurrent pregnancy loss: current perspectives.&nbsp;International journal of women's health,&nbsp;9, 331–345. <a href="https://doi.org/10.2147/IJWH.S100817" target="_blank" rel="noopener">https://doi.org/10.2147/IJWH.S100817</a>

Danielsson, K. (2020). How a septate uterus increases miscarriage risk. VeryWellFamily

Ford, H. B., &amp; Schust, D. J. (2009). Recurrent pregnancy loss: etiology, diagnosis, and therapy.&nbsp;Reviews in obstetrics &amp; gynecology,&nbsp;2(2), 76–83.

Синдром на Ашерман – сраствания в маточната кухина - bg

Care England. Uterine Fibroids, Polyps &amp; Abnormalities. womenandinfants.org

Raj, Raj, Backos, M., Rushworth, F., Regan, L. (2000). Polycystic ovaries and recurrent miscarriage—a reappraisal,&nbsp;Human Reproduction, Volume 15, Issue 3, Pages 612–615,&nbsp;<a href="https://doi.org/10.1093/humrep/15.3.612" target="_blank" rel="noopener">https://doi.org/10.1093/humrep/15.3.612</a><a href="https://pubmed.ncbi.nlm.nih.gov/14669168/" target="_blank" rel="noopener">https://pubmed.ncbi.nlm.nih.gov/14669168/</a>

Mills, J. L. et al. (1988). Incidence of spontaneous abortion among normal women and insulin-dependent diabetic women whose pregnancies were identifies within 21 days of conception. The New England Journal of Medicine. 319:1617-1623. DOI: 10.1056/NEJM198812223192501

Thyroid Disorders and Pregnancy | Children's Hospital of Philadelphia

Di Prima, F. A. et al. (2011). Antiphospholipid Syndrome during pregnancy: the state of the art.&nbsp;Journal of prenatal medicine,&nbsp;5(2), 41–53.

W. Tang, Z. Alfirevic, S. Quenby, Natural killer cells and pregnancy outcomes in women with recurrent miscarriage and infertility: a systematic review,&nbsp;Human Reproduction, Volume 26, Issue 8, August 2011, Pages 1971–1980,&nbsp;<a href="https://doi.org/10.1093/humrep/der164" target="_blank" rel="noopener">https://doi.org/10.1093/humrep/der164</a>

Kwak, J.Y., Beer, A.E., Kim, S.H. and Mantouvalos, H.P. (1999), Immunopathology of the Implantation Site Utilizing Monoclonal Antibodies to Natural Killer Cells in Women with Recurrent Pregnancy Losses. American Journal of Reproductive Immunology, 41: 91-98.&nbsp;<a href="https://doi.org/10.1111/j.1600-0897.1999.tb00080.x" target="_blank" rel="noopener">https://doi.org/10.1111/j.1600-0897.1999.tb00080.x</a>

Rasch, V. (2003), Cigarette, alcohol, and caffeine consumption: risk factors for spontaneous abortion. Acta Obstetricia et Gynecologica Scandinavica, 82: 182-188.&nbsp;<a href="https://doi.org/10.1034/j.1600-0412.2003.00078.x" target="_blank" rel="noopener">https://doi.org/10.1034/j.1600-0412.2003.00078.x</a>

Cnattingius, et al. (2000). Caffeine Intake and the Risk of First-Trimester Spontaneous Abortion. New England Journal of Medicine. 343.25. Pages 1839-1845. DOI: 10.1056/NEJM200012213432503

Robinson, L., et al. (2012). The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis,&nbsp;Human Reproduction, Volume 27, Issue 10, Pages 2908–2917,&nbsp;<a href="https://doi.org/10.1093/humrep/des261" target="_blank" rel="noopener">https://doi.org/10.1093/humrep/des261</a>

Антитиреоидни антитела ТАТ МАТ. Reproinova.com

Feng, Ye &amp; Yang, H. (2017) Metformin – a potentially effective drug for gestational diabetes mellitus: a systematic review and meta-analysis,&nbsp;The Journal of Maternal-Fetal &amp; Neonatal Medicine,&nbsp;30:15,&nbsp;1874-1881,&nbsp;DOI:&nbsp;<a href="https://doi.org/10.1080/14767058.2016.1228061" target="_blank" rel="noopener">10.1080/14767058.2016.1228061</a>

Най-чести причини за повтаряща се загуба на бременност

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 Най-чести причини за повтаряща се загуба на бременност

Ивелина Янкова

Herbal and Natural Medicine  - билковата енциклопедия във вашия джоб

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 Herbal and Natural Medicine - билковата енциклопедия във вашия джоб

Силвия Маринова

История на джина

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Quinine_an_old_anti_malarial_drug_in_a_modern_world_role_in_the_treatment_of_malaria_21609473" target="_blank" rel="noopener">Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria. </a>2011, Malar J

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/A_Phytopharmacological_Review_on_a_Medicinal_Plant_Juniperus_communis_27419205" target="_blank" rel="noopener">A Phytopharmacological Review on a Medicinal Plant: Juniperus communis</a>., 2014, International scholarly research notices

Полезните свойства на хвойната - тайната на джина 

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 Полезните свойства на хвойната - тайната на джина

Review of Pharmacological Properties and Chemical Constituents of Pimpinella anisum, 2012, ISRN Pharm.

In vitro Antibacterial activity of Pimpinella anisum fruit extracts against some pathogenic bacteria, 2008, Veterinary world

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Antifungal_activity_of_fluid_extract_and_essential_oil_from_anise_fruits_Pimpinella_anisum_L_Apiaceae_16375827" target="_blank" rel="noopener">Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae).</a> 2005, Acta Pharm.

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/The_fruit_essential_oil_of_Pimpinella_anisum_exerts_anticonvulsant_effects_in_mice_10433480" target="_blank" rel="noopener">The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice. </a>1999, Journal of Ethnopharmacology

The fruit essential oil of Pimpinella anisum L. (Umblliferae) induces neuronal hyperexcitability in snail partly through attenuation of after-hyperpolarization, 2008, Journal of Ethnopharmacology

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Aqueous_suspension_of_anise_Pimpinella_anisum_protects_rats_against_chemically_induced_gastric_ulcers_17373749" target="_blank" rel="noopener">Aqueous suspension of anise "Pimpinella anisum" protects rats against chemically induced gastric ulcer</a>s, 2007, World Journal of Gastroenterology

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Antispasmodic_and_relaxant_effects_of_the_hidroalcoholic_extract_of_Pimpinella_anisum_Apiaceae_on_rat_anococcygeus_smooth_muscle_17027208" target="_blank" rel="noopener">Antispasmodic and relaxant effects of the hidroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle</a>., 2007, Journal of Ethnopharmacology

Анасонът - древната билка с летен вкус

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 Анасонът - древната билка с летен вкус

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Horse_chestnut_seed_extract_for_chronic_venous_insufficiency_23152216" target="_blank" rel="noopener">Horse chestnut seed extract for chronic venous insufficiency</a>, 2012, Cochrane Database Syst Rev

Natural Standard Herb &amp; Supplement Guide - E-Book An Evidence-Based Reference, 2010, St Louis: Elsevier Health Sciences

Макар и не за домашна употреба, някои екстракти от лечебни растения дават надежда за неоперативното или поддържащо лечение на разширени вени. Въпрос на време е екстрактите да станат лесно достъпни за тези, които се нуждаят от тях.

Лечебни растения, които може да ви помогнат при разширени вени

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 Лечебни растения, които може да ви помогнат при разширени вени

Rositsa Tashkova-Kacharova

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Complementary_and_integrative_treatments_rhinosinusitis_23764814" target="_blank" rel="noopener">Complementary and Integrative Treatments: Rhinosinusitis</a>, 2013

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Chemistry_and_bioactivity_of_Flos_Magnoliae_a_Chinese_herb_for_rhinitis_and_sinusitis_18673228" target="_blank" rel="noopener">Chemistry and bioactivity of Flos Magnoliae, a Chinese herb for rhinitis and sinusitis</a>, 2008, Current Medicinal Chemistry

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Pelargonium_sidoides_extract_for_treating_acute_respiratory_tract_infections_24146345" target="_blank" rel="noopener">Pelargonium sidoides extract for acute respiratory tract infections</a>, 2014, Cochrane Database Syst Rev

Колкото и безнадеждно да се чувства човек, когато има синузит, както съвременната, така и традиционната медицина няма да го оставят безпомощен. Комбинацията от методи под лекарски контрол ще донесе облекчение и ще излекува инфекцията. Но към синузита не бива да се подхожда с лека ръка, тъй като той представлява възпаление и то в кухини, разположени в главата. Неизлекуваният синузит лесно може да хронифицира и да се появява отново и отново цял живот. Затова е важно да следваме препоръките на специалистите и да се справим с инфекцията възможно най-скоро.

Синузит: природни и домашни средства за справяне с дискомфорта

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 Синузит: природни и домашни средства за справяне с дискомфорта

Magnesium, Fact Sheet for Health Professionals, NIH

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Inhibitory_effects_of_zinc_on_magnesium_balance_and_magnesium_absorption_in_man_7836627" target="_blank" rel="noopener">Inhibitory effects of zinc on magnesium balance and magnesium absorption in man</a>, 1994, J Am Coll Nutr

Магнезият е един от най-важните минерали за човешкото тяло. Той участва в стотици процеси в нас и липсата му е свързана с редица заболявания. Набавянето на достатъчни количества магнезий не е трудно и се постига чрез правилно хранене или прием на добавки и лекарства.

Магнезий - как да си го набавим с природни средства и до какво води дефицитът

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 Магнезий - как да си го набавим с природни средства и до какво води

CHAPTER 13 - Pregnancy: First Trimester, 2010, Botanical Medicine for Women's Health

Herbal Tea and Pregnancy, American Pregnancy Association

The Effects of Combined Low-Dose Oral Contraceptives and Vitex Agnus on the Improvement of Clinical and Paraclinical Parameters of Polycystic Ovarian Syndrome: A Triple-Blind, Randomized, Controlled Clinical Trial, Iranian Red Crescent Medical Journal inpress, 2016

Съществуват билки с доказани полезни за женското здраве ефекти. Те могат да бъдат използвани след консултация с лекар и в зависимост от нуждите и състоянието на всяка отделна жена. Списъкът не е изчерпателен - повече за билките, които облекчават симптомите на менопаузата, при поликистозни яйчници и бременност ще откриете в цитираните по-горе статии от екипа на Санацио.&nbsp;

6 билки в помощ на женското здраве

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 6 билки в помощ на женското здраве

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Curcumin_from_ancient_medicine_to_current_clinical_trials_18324353" target="_blank" rel="noopener">Curcumin: from ancient medicine to current clinical trials</a>, 2008, Cellular and Molecular Life Sciences

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Curcumin_the_Indian_solid_gold_17569205" target="_blank" rel="noopener">Curcumin: the Indian solid gold</a>, 2007, Advances in Experimental Medicine and Biology

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Health_promoting_properties_of_artichoke_in_preventing_cardiovascular_disease_by_its_lipidic_and_glycemic_reducing_action_23923586" target="_blank" rel="noopener">Health-promoting properties of artichoke in preventing cardiovascular disease by its lipidic and glycemic-reducing action</a>, 2013, Monaldi Archives for Chest Disease

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Recent_advances_in_the_analysis_of_flavonolignans_of_Silybum_marianum_27321822" target="_blank" rel="noopener">Recent advances in the analysis of flavonolignans of Silybum marianum</a>, 2016, Journal of Pharmaceutical and Biomedical Analysis

<a href="https://www.bioseek.eu/bg/bul/research/pubmed/Comparison_between_Lysimachiae_Herba_and_Desmodii_Styracifolii_Herba_in_pharmacological_activities_26552164" target="_blank" rel="noopener">Comparison between Lysimachiae Herba and Desmodii Styracifolii Herba in pharmacological activities</a>, 2015, Zhongguo Zhongyao Zazhi