colon

Health-benefits-of-sweet-potatoes-(Ipomoea-batatas)

Health benefits of sweet potatoes (Ipomoea batatas)

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Sweet potatoes (Ipomoea batatas) &nbsp;<a href="https://www.herbal-organic.com/bg/herb/14493" target="_blank" data-ref="Sweet potato" rel="noopener">[ref. 1]</a>&nbsp; are usually recognized by their copper-colored bark and bright orange color. In fact, there are other varieties grown all over the world, with colors such as white, creamy, yellow, reddish-purple, and saturated purple.&nbsp;

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True to their name, sweet potatoes have a naturally sweet taste, which is further enhanced by cooking methods such as baking. They are also one of the best sources of beta-carotene - a precursor to vitamin A. Sweet potatoes contain plenty of other carotene pigments. In some studies, sweet potatoes have been shown to be a better source of bioavailable beta-carotene than green leafy vegetables. Carotenoids are also antioxidants, which means they have the power to protect <a href="https://www.mdpi.com/2076-3921/7/2/28" target="_blank" data-ref="Carotenoids&mdash;Antioxidant Properties" rel="noopener">your cells from daily damage.</a>&nbsp;[ref. 2]&nbsp;

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Ipomoea batatas are also sources of anti-inflammatory nutrients, soluble and insoluble fiber, and other beneficial components of different actions.&nbsp;

Vitamins-and-minerals-in-abundance

Vitamins and minerals in abundance 

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Only one sweet potato gives you 400% of the vitamin A you need every day. This helps to keep your eyes healthy as well as the immune system in optimal conditioning. Also, vitamin A is useful for the reproductive system and organs such as the heart and kidneys.&nbsp;

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Sweet potatoes are rich in the following nutrients:

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<ul><li style="font-weight: 400;" aria-level="1">Vitamins of group B</li><li style="font-weight: 400;" aria-level="1">Vitamin C</li><li style="font-weight: 400;" aria-level="1">Calcium</li><li style="font-weight: 400;" aria-level="1">Iron</li><li style="font-weight: 400;" aria-level="1">Magnesium</li><li style="font-weight: 400;" aria-level="1">Phosphorus</li><li style="font-weight: 400;" aria-level="1">Potassium</li><li style="font-weight: 400;" aria-level="1">Thiamin</li><li style="font-weight: 400;" aria-level="1">Zinc</li></ul>

Sweet-potatoes-for-gut-health

Sweet potatoes for gut health 

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Fiber and antioxidants in sweet potatoes are good for gut health. Sweet potatoes contain two types of fiber: soluble and insoluble. &nbsp;<a href="https://pubs.acs.org/doi/10.1021/jf101021s" target="_blank" data-ref="Just a moment..." rel="noopener">[ref. 3]</a>&nbsp; These components contribute to good peristalsis and regular bowel movements, and maintenance of digestive function and processes.

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In this regard, in vitro studies have found that antioxidants in several types of sweet potatoes promote the growth of beneficial gut bacteria, including certain types of Bifidobacterium and Lactobacillus. &nbsp;<a href="https://www.nature.com/articles/s41598-018-23397-0?error=cookies_not_supported&amp;code=04a275e3-d327-4e3a-b8b6-cac8bfe2178e" target="_blank" data-ref="Antioxidant and prebiotic activity of five peonidin-based anthocyanins extracted from purple sweet potato (Ipomoea batatas (L.) Lam.) - Scientific Reports" rel="noopener">[Ref. 4]</a>&nbsp;

Potential-anticancer-properties-of-sweet-potatoes

Potential anticancer properties of sweet potatoes 

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Sweet potatoes provide a variety of antioxidants that can help protect against certain cancers. Anthocyanins - a group of antioxidants found in purple sweet potatoes - can slow down the growth of certain types of cancer cells in in vitro studies, including those of bladder, colon, stomach and breast cancer. &nbsp;<a href="https://www.hindawi.com/journals/bmri/2015/768093/" target="_blank" data-ref="Anti-Inflammatory and Anticancer Activities of Taiwanese Purple-Fleshed Sweet Potatoes (Ipomoea batatas L. Lam) Extracts" rel="noopener">[Ref. 5]</a>&nbsp;

Sweet-potatoes-for-normal-brain-function

Sweet potatoes for normal brain function 

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Animal studies have found that anthocyanins can protect the brain by reducing inflammation and preventing damage from free radicals. It is important to note that no studies have been conducted to test these effects in humans, but overall diets rich in fruits, vegetables and antioxidants are associated with a 13% lower risk of cognitive decline and dementia.

How-to-cook-a-sweet-potato

How to cook a sweet potato 

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First of all, it is important to clean sweet potatoes before use if you leave the crust for a certain recipe. If you're not going to cook them right after peeling or chopping, dip them in cold water to prevent discoloration.

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Sweet potatoes are a great alternative to classic potatoes in most recipes. They can be cooked, roasted, or stewed until softened, then blended, pureed, or simply served with spices.

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Baked sweet potato, like a baked potato, should be cooked in a medium-hot oven for about 45 minutes. For a microwave, prepare like a baked potato, but cook over high heat for 10 minutes, turning once during cooking. Grilling sweet potatoes is another great method that will accentuate their great taste.

What-foods-get-along-with-sweet-potatoes

What foods get along with sweet potatoes 

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Sweet potatoes partner well with spicy flavors, so they can be a side dish seasoned with curry powder, cumin, chili, black pepper, paprika, citrus juice, and ginger, as well as cinnamon and nutmeg. Iron-rich spinach and earthy beetroot suit the natural sweetness of potatoes, as well as meat with a strong taste such as lamb and duck.

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Making sweet potatoes with a little fat - such as coconut oil, olive oil or avocado oil - can help increase the absorption of beta-carotene, as it is a fat-soluble nutrient.&nbsp;

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As long as you know how to cook them, sweet potatoes are a great alternative to the usual potatoes in culinary. Compatible with almost any diet, they can be cooked in many ways and matched with vegetables and meat, and have great health benefits. Rich in nutrients, and antioxidants, and with potentially anti-cancer effects, sweet potatoes are a great food to consume whenever possible.

Health Benefits of Sweet Potatoes (Ipomoea batatas)

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Бетина Цветкова

Sea-snail-goo---how-it-can-help

Sea snail goo - how it can help

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Crimson mucus, which the Australian sea snail produces to protect its eggs, contains a compound that could one day prevent colon cancer in humans. This is claimed by researchers from Australia's Flinders University, Southern Cross University and Monash University.

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In a study published in Nature Scientific Reports, the researchers detailed the mechanisms in Muricidae mollusks. [Ref.&nbsp;<a href="https://www.nature.com/articles/s41598-019-48533-2?error=cookies_not_supported&amp;code=70964f61-06a4-49cc-a013-a6ed6aaa5f6c" target="_blank" data-ref="Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging - Scientific Reports" rel="noopener">1]</a>&nbsp; They possess a gland that secretes a compound belonging to a class called indoli , organic compounds found in herbal medicines and pharmaceutical drugs. Although it is known that this compound has antibacterial and anti-inflammatory properties, scientists are not sure that it can be an effective cancer treatment of 100%.

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To find out more about the issue, the team exposed extracts from the compound to human cancer cell lines. This establishes that it kills cancer cells. The scientists then carried out a set of experiments in which mice were given an extract, as well as carcinogens, to cause cancer. Using mass spectrometry, the team tracked the extract as it moved through the mice' organisms and eventually to the colon, where it prevented tumor formation.

The-findings-of-the-team-of-scientists

The findings of the team of scientists 

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The research team from the three universities was able to take advantage of the fact that snail compounds contain bromine as a unique fingerprint. This tracks how these types of compounds are metabolized in the body and identify some potentially toxic metabolites from raw extracts that have not been found in the pure snail compound. This study is very important for understanding the safety of these types of natural compounds for human medicine.

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For years, scientists have known that sea snails produce a compound that is unusually effective at killing both normal and drug-resistant cancer cells. But the new study is unique because it shows that tumors can actually be prevented.

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According to Katherine Aber, a professor of molecular biology at Flinders University and author of the study, scientists were able to enter a colorectal cancer model long-term. They managed to show that one of the compounds in the extract, 6-Br, is able to reduce tumors. Previously, only their effects were considered in a period of six hours after damage to the DNA of a cell of the colon.

What's-next

What's next

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The team hopes their findings will someday improve treatment for colorectal cancer, which causes the deaths of 862,000 people in 2018 and is the second leading cause of death from cancer, according to the World Health Organization. &nbsp;<a href="https://www.who.int/news-room/fact-sheets/detail/cancer" target="_blank" data-ref="Cancer" rel="noopener">Although it will take years</a>&nbsp;before the compound becomes part of a widespread treatment, the findings highlight how cancer researchers have only just begun to explore a huge resource of potential cures found in the world's oceans.

Surprisingly or not, over 50 percent of the drugs used to treat cancer and more than 75 percent of the drugs used to treat infectious diseases are derived from natural products. Probably, something similar will be developed for some forms of cancer based on sea snail goo. There is a long way to go in the scientific work of the researchers, and it remains for us to believe that the marine environment hides other potential remedies for human diseases.

Sea snail mucus goo could prevent colorectal cancer, study says

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What-is-Crohn's-disease

What is Crohn's disease

What-is-Crohn's-disease_0_0

Crohn's disease is a chronic or long-term condition that causes inflammation in the digestive tract. It is an autoimmune mediated inflammatory condition, that is, induced by autoimmune in the body. Therefore, the reasons should be sought in the activity of the thyroid gland, adrenal glands, hormonal values, and in general - to analyze the endocrine, digestive, immune, nervous systems.

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Symptoms of Crohn's disease vary depending on which part of the intestine affects the condition. These often include pain syndrome, bowel ulcers, diarrhea, fatigue and exhaustion, weight loss and anemia, brain fog and others. With exacerbation of the condition, arthritis, skin disorders, inflammation of the liver and others may be triggered.

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After extensive diagnosis and confirmation of the disease follow guidelines for nutrition and medications. Alternative medicine funds may be added to them to support therapy.

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Recommended-herbs-and-supplements-for-Crohn's-disease

Recommended herbs and supplements for Crohn's disease

Boswellia

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One natural remedy that has been studied to relieve digestive disorders is Boswellia serrata&nbsp;<a href="https://www.herbal-organic.com/bg/herb/15122" target="_blank" data-ref="Boswellia serrata" rel="noopener">[ref. 1]</a>&nbsp; Boswellia supplements are extracted from trees that produce sweet-looking resin rich in carbohydrates, essential oils and boswellic acid. Acid in resin is the active ingredient. It is believed to act as an anti-inflammatory agent.

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A recent study found that 14 out of 20 people with Crohn's disease who received Boswellia supplements achieved remission. However, this study is far from sufficient to offer definitive conclusions about the action of boswellia.&nbsp;

Turmeric

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Turmeric is a spice that is a relative of ginger. &nbsp;<a href="https://www.herbal-organic.com/bg/herb/14445" target="_blank" data-ref="Curcuma" rel="noopener">[Ref. 2]</a>&nbsp; Studies covering the past two decades have suggested that curcumin, a compound found in turmeric, has several healing properties that may be beneficial for people with Crohn's disease. We are talking about anti-inflammatory, anticancer, antiamiloid properties and antiarticular properties.

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In addition, turmeric has antioxidant properties and is an antimicrobial agent. Therefore, it can help to fight infections in people with <a href="http://www.eurekaselect.com/article/54792" target="_blank" data-ref="Curcumin: A Boon to Colonic Diseases" rel="noopener">Crohn's disease</a>.&nbsp;[ref. 3]&nbsp;

Green-tea

Green tea

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Camellia Sinensis tea is a popular drink worldwide. &nbsp;<a href="https://www.herbal-organic.com/bg/herb/14489" target="_blank" data-ref="Camellia sinensis" rel="noopener">[ref. 4]</a>&nbsp;Rich in antioxidants and polyphenols, green tea has become known as a means of supporting digestion and weight loss. However, more in-depth research is needed for its effects on the intestines and colon.

N-Acetylglucosamine

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N-acetylglucosamine is a supplement that is most often extracted from mussels. In some tests it is associated with success in the treatment of autoimmune diseases. N-acetylglucosamine can stop the activity of cells that cause inflammation.

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In one study it became clear that supplements with N-acetylglucosamine reduce colon inflammation in children with Crohn's disease without negative side effects. &nbsp;<a href="https://onlinelibrary.wiley.com/resolve/doi?DOI=10.1046/j.1365-2036.2000.00883.x" target="_blank" data-ref="Just a moment..." rel="noopener">[Ref. 5]</a>&nbsp;

Vitamin-D

Vitamin D

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Recent studies have shown that vitamin D may be useful in the treatment of Crohn's disease. In them very often this vitamin is in short supply. By including sources of vitamin D, people with Crohn's disease can control symptoms and improve immune system health.&nbsp;

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This is the solar vitamin, so sun exposure is one source. Foods such as fish, seafood, eggs and others are dietary sources. Additionally, supplements with cholecalciferol (vitamin D3)- an active form of vitamin D can be taken.

Since Crohn's disease develops with a compromised immune system and activation of autoimmunity, it should be carefully evaluated what herbs and supplements to take. This must necessarily be done by medical discretion and in view of the state of play, possible other diseases and other factors.&nbsp;

Crohn's disease: Recommended Herbs and Dietary Supplements

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Colorectal-cancer---what-is-the-disease

Colorectal cancer - what is the disease 

Colorectal-cancer---what-is-the-disease_0_0

Often, both colon and rectal cancers are combined into a common concept of "colorectal cancer". This is a term that represents the third most common form of cancer in the world. But they are not the same thing and are not interchangeable. ( <a href="https://www.mdpi.com/1422-0067/19/9/2577" target="_blank" data-ref="Are Colon and Rectal Cancer Two Different Tumor Entities? A Proposal to Abandon the Term Colorectal Cancer" rel="noopener">[ref. 1]</a>&nbsp;)

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Colon cancer describes the existence of cancer cells in the colon, while rectal cancer describes cancer in the rectum. Rectal cancer is less common than colon cancer and is more difficult to treat. Common symptoms include rectal bleeding, constipation and abdominal pain.&nbsp;

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In terms of the degree of remission, it can be high if the disease is detected early. When rectal cancer is localized, the five-year survival rate is 90%. If it has spread a little, the percentage decreases to 73%, and if it is many, the percentage drops to 17%.

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Clinical-study-of-a-drug-for-rectal-cancer

Clinical study of a drug for rectal cancer  

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Each of the patients in this recent study had a very specific form of rectal cancer called "rectal adenocarcinoma with a recovery mismatch." This form of cancer is even more difficult to treat than general rectal cancer.

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After receiving an experimental drug called dostarlimab- anti-PD-1 monoclonal antibody, all successfully treated 12 participants underwent complete remission. Doctors say this is the first time such cancer drug has had 100% success in a clinical trial. [ <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2201445" target="_blank" data-ref="PD-1 Blockade in Mismatch Repair&ndash;Deficient, Locally Advanced Rectal Cancer | NEJM" rel="noopener">[ref. 2]</a>&nbsp;

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The results of the small study, carried out by researchers at memorial Sloan Kettering Cancer Center in New York, were published in the renowned journal New England Journal of Medicine. The results of the study were funded by the pharmaceutical company GlaxoSmithKline.&nbsp;

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Other similar studies have been conducted in the past, such as a clinical trial led by Dr. Luis A. Diaz Jr. in 2017, which Merck , the drug maker, has funded. It involves 86 people with metastatic cancer, which originates from different parts of their bodies. But all cancers share a gene mutation that prevents cells from repairing DNA damage. These mutations occur in 4% of all cancer patients. Patients in this study took an inhibitor of Merck's checkpoint, pembrolizumab, for up to two years. Tumors shrink or stabilize in about a third to half of patients, and they live longer. Also, the tumors disappeared in 10% of the study participants.

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Participants in the new 2022 clinical trial were patients with rectal cancer and faced exhausting forms of treatment - chemotherapy, radiation and most likely life-changing surgery that could lead to intestinal, urinary and sexual dysfunction. They comply to be part of the trial, because they think that they will go all over again with the process and no one expected their tumors to disappear. Patients receive the drug intravenously every three weeks for six months, with a cost of about $11,000 per dose. The drug works by demasking cancer cells, allowing the immune system to identify and destroy them. It is a form of immunotherapy that promotes the body's own immune system to work as an ally against cancer. The MSK clinical trial is investigating - for the first time - whether immunotherapy alone can beat rectal cancer that has not spread to other tissues in a subset of patients whose tumor contains a specific genetic mutation.&nbsp;

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Helping-the-immune-system-overcome-rectal-cancer

Helping the immune system overcome rectal cancer

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Immune cells contain a precaution called a checkpoint so that normal cells do not attack them. (&nbsp;<a href="https://www.memorial.com.tr/bg/treatment-modalities/immunotherapy-what-is-it" target="_blank" data-ref="Just a moment..." rel="noopener">[ref. 3]</a> Cancer cells can trigger this defense and turn off immune cells, allowing the tumor to hide and grow. However, immunotherapy can turn the tide again.

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An immunotherapy agent called a checkpoint inhibitor releases the brake on the immune cell, allowing it to recognize and attack cancer cells. When the brakes are taken off the immune cells, the MMRd cells look particularly strange because they have so many mutations. Thus, the immune cells attack with much greater force. Dr. Diaz's pioneering research in cancer immunotherapy has already shown that checkpoint inhibitors can help people with MMRd colorectal tumors that have spread. ( [ref. 4] Thus, together with the team, they came up with the idea of ​​applying immunotherapy as a first-line treatment before the cancer has metastasized.

The-result:-100%-remission-of-rectal-cancer

The result: 100% remission of rectal cancer 

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Although a small study with only 18 patients with rectal cancer successfully passed from them 12, each of whom took the same drug and the results are stunning. Amazingly, the cancer disappears in every single patient, it is not detected and on physical examination; endoscopy; positron emission tomography or PET scan, nor in MRI scans (MRI resonance imaging). The results are so impressive that they were published in The New England Journal of Medicine and presented at the largest gathering of clinical oncologists in the country in June 2022.&nbsp;

Side-effects-in-the-treatment-of-rectal-cancer

Side effects in the treatment of rectal cancer

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<h2>&nbsp;</h2>None of the patients had a relapse of the disease or needed additional treatment during a follow-up period that lasted an average of about a year, the study said.

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In addition, none of the 12 patients had serious side effects, which is one of the main problems in typical treatments for rectal cancer and other cancers (such as chemotherapy or radiotherapy).&nbsp;

A small study gives hope to people with rectal cancer and probably for everyone else with this condition. In a small trial, 100% of the participants were cured with the help of a form of immunotherapy received intravenously. The scientific team reports that the clinical trial continues to involve patients and is spreading out, and the side effects of the therapy are absent and no relapse is observed.&nbsp;

For the first time in a clinical trial: remission in every patient with rectal cancer

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For the first time in a clinical trial: remission in every patient with p

What-is-acerola-cherry?

What is acerola cherry?

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Acerola Cherry (Malpighia glabra) is a plant that originates in America. [ <a href="https://www.herbal-organic.com/bg/herb/17678" target="_blank" data-ref="Malpighia glabra" rel="noopener">[ref. 1]</a> ] The bush blooms from April to November, with the fruits ripening 3-4 weeks after flowering. It gives cherries which are 1-4 cm in diameter. At first they look green, then switch to orange-red and reach the final bright red color at full ripening.

What-is-Acerola-Cherry-useful-for?

What is Acerola Cherry useful for?

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Besides containing a huge amount of vitamin C,&nbsp; acerola cherries contain other beneficial nutrients.

Rich-in-vitamin-C

Rich in vitamin C

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Vitamin C is necessary for immune function, collagen production and carnitine synthesis, which plays a role in transforming fat into energy. Vitamin C also plays a role in the production of neurotransmitters, which in turn are involved in the normal function of the nervous, cerebral and other systems.&nbsp;

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Due to the extremely rich amount of vitamin C, acerola is often used to help or prevent a cold or flu. It has more vitamin C than blackcurrant and rosehip.

Phytonutrients

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Phytonutrients identified in the acerola cherry include carotenoids, phenols, flavonoids and anthocyanins, which have antioxidant properties. [ <a href="https://www.herbal-organic.com/bg/pubmed/HPLC_and_in_vitro_evaluation_of_antioxidant_properties_of_fruit_from_Malpighia_glabra_Malpighiaceae_at_different_stages_of_maturation_29180061" target="_blank" data-ref="HPLC and in vitro evaluation of antioxidant properties of fruit from Malpighia glabra (Malpighiaceae) at different stages of maturation. | Билкови и природни лекарства" rel="noopener">[ref. 2]</a>&nbsp;]

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The fruit also contains provitamin A as carotenoids, which means they are transformed into vitamin A when the body needs nutrients. Other vitamins contained in acerola are B1, B2, B3, plus minerals iron, phosphorus, and calcium.&nbsp;

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The main phenols present in acerola are in the form of phenolic acids, flavonoids and anthocyanins. These compounds are useful for combating oxidative damage, along with antioxidant nutrients. Phenolic compounds are one of the key secondary metabolites that have a variety of structures and subsequently a variety of useful functions present ubiquitously in plants.&nbsp;

Rich-content-of-pectin

Rich content of pectin

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Acerola cherry can support digestive health. Pectin is a soluble dietary fiber, methylated ester of polylacturonic acid, which makes up about a third of the dry matter of the cell wall in the fruits of acerola and exerts a powerful prebiotic effect.&nbsp;

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Prebiotic fibers are fermented by beneficial bacteria present in the colon to produce beneficial compounds that maintain immunity and signal beneficial actions throughout the body. [&nbsp;<a href="https://academic.oup.com/cdn/article/2/3/nzy005/4828321" target="_blank" data-ref="Health Effects and Sources of Prebiotic Dietary Fiber" rel="noopener">[ref. 3]</a>&nbsp;]

Is-acerola-cherry-more-useful-than-ascorbic-acid?

Is acerola cherry more useful than ascorbic acid?

Is-acerola-cherry-more-useful-than-ascorbic-acid?_1_0

When a food is consumed in its original state (instead of processed), the body can absorb more nutrients. In the case of cherry acerola, especially if the fruit is organic, the nutritional content is much richer and provides many other substances other than vitamin C.&nbsp;

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In addition, there are additional nutritional benefits from eating fruit. The fruit will provide bioflavonoids, minerals, vitamins, trace elements, as well as useful organic acids. It is known that these nutrients work in synergy with vitamin C in terms of absorption and activity.&nbsp;

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How-to-take-acerola?

How to take acerola?

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If possible, consumption of the fruit part of the acerola plant is recommended. Its taste is usually described as sweet, fragrant and a astringent. It is easy to eat acerola raw or prepared in dishes.

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The best way to get the fruits is to grow on your own, because cherry acerola quickly spoils. You can also keep fresh acerola cherries by freezing them as soon as you gather them.

Acerola cherries contain 30 times more vitamin C than oranges and have more vitamin C than other fruits such as blackcurrant and rosehip. Rich in essential nutrients including carotenoids, B vitamins, vitamin A, flavonoid minerals and anthocyanins, acerola fruit is a great addition to a healthy diet. Only should not overdo it with the amount, since this natural immunostimulant can upset the gastrointestinal tract.