Fatigue is a feeling of tiredness. It may be sudden or gradual in onset. It is a normal phenomenon if it follows prolonged physical or mental activity, and resolves completely with rest. However, it may be a symptom of a medical condition if it is prolonged, severe, progressive, or occurs without provocation.

Physical fatigue is the transient inability of muscles to maintain optimal physical performance, and is made more severe by intense physical exercise. Mental fatigue is a transient decrease ...

fatigue

What-is-the-thyroid-gland

What is the thyroid gland

What-is-the-thyroid-gland_0_0

What-is-the-thyroid-gland_0_1

It may be small in size, but the butterfly-shaped gland, which is located in the neck area, has indispensable health functions. Your thyroid gland is responsible for producing thyroid hormone (TH), which regulates, among other things, the body's temperature, metabolism, and heart rate.&nbsp;

What-is-the-thyroid-gland_0_2

Things can start to go wrong when the thyroid gland is with hyper or hypofunction due to various factors. If it is with decreased function - hypofunction, when it produces too little TH; Alternatively, if it has an increased function - hyperfunction, then it produces too much of this hormone. In addition, other hormones, such as LH, FSH, as well as antibody levels, also serve as a comprehensive factors of the actual condition.

What-is-the-thyroid-gland_0_3

But what makes your thyroid gland out of balance? The factors may be genetic, autoimmune processes may take place in the body. Impaired thyroid function can also occur during pregnancy, stress, nutritional deficiencies or accumulation of toxins in the environment. And while the hypofunction tends to attract more attention among scientists, there's also the opposite situation where we're talking about an overactive thyroid. It should also be taken into account, since the effects of an overactive thyroid gland are related to weight, overall hormonal background, reproductive abilities, ability to concentrate, memory and others.

Hyperfunction-and-hypofunction---two-sides-of-an-impaired-thyroid-function

Hyperfunction and hypofunction - two sides of an impaired thyroid function

10-signs-of-hyperthyroidism

10 signs of hyperthyroidism 

10-signs-of-hyperthyroidism_1_0

10-signs-of-hyperthyroidism_1_1

As mentioned, hyperthyroidism is an overactive thyroid. When this happens, the body produces an excess of thyroid hormones, such as triiodothyronine (T3) and thyroxine (T4). T4 is produced specifically when the pituitary gland secretes thyroid-stimulating hormone (TSH). Here are the signs that your thyroid is working at an elevated speed and producing abnormally high levels of thyroid hormones: &nbsp;<a href="https://linkinghub.elsevier.com/retrieve/pii/S0140673616002786" target="_blank" data-ref="Redirecting" rel="noopener">[Ref. 1]</a>&nbsp;

10-signs-of-hyperthyroidism_1_2

Nervousness and anxiety&nbsp; - When the thyroid gland works excessively, hormones tell the body to work even harder. This leads to several symptoms that can make you feel nervous and anxious. But before that, these hormones lead to mood swings and racing thoughts.&nbsp;

10-signs-of-hyperthyroidism_1_3

Fast heart rate (plus palpitations) - As one of the physical symptoms of high hormone levels, your heart rate may increase. An increase in heart rate can also lead to palpitations. So, if you feel that the heart is undergoing any unusual changes, be sure to seek medical attention.&nbsp;

10-signs-of-hyperthyroidism_1_4

Increased sweating - Because thyroid hormones tell your body to become more active, naturally it will try to cool itself by sweating, even in less active situations when you're not physically active.&nbsp;

10-signs-of-hyperthyroidism_1_5

Weight loss - Although this effect is usually sought with other methods, hyperfunction is possible, but with adverse consequences. The abundance of thyroid hormones will speed up your metabolism and appetite. Although you may notice unexplained weight loss, it can lead to dramatic and unwanted changes related to the type of skin, hair, nails, joints and muscles.

10-signs-of-hyperthyroidism_1_6

Change in peristalsis - Changes in hormone levels can even affect your digestive system. More frequent bowel movements may indicate other conditions, such as Crohn's disease or problems with gluten absorption or lactose intolerance.&nbsp;

10-signs-of-hyperthyroidism_1_7

Goiter - Goiter occurs when the thyroid gland begins to enlarge due to the overproduction of hormones. Normally, the thyroid gland needs adequate levels of iodine, which we should get from the diet. However, if you do not have enough iodine, your body will try to compensate for what is missing, and the thyroid gland will enlarge. If you develop a goiter, you should take iodine supplements after consulting a specialist to suggest other personalized medical solutions.

10-signs-of-hyperthyroidism_1_8

You should also keep in mind that Hashimoto's thyroiditis often causes goiter. It is an autoimmune disease that affects millions of people around the world, mainly women. Specifically, this disease causes inflammation and damage to the thyroid gland. As a result of Hashimoto's, the body tries to compensate by triggering thyroid growth and a host of different symptoms affecting joints, skin, hair, and other aspects. &nbsp;<a href="https://www.frontiersin.org/articles/10.3389/fendo.2018.00737/full" target="_blank" data-ref="The Pathology of Hyperthyroidism" rel="noopener">[ref. 2]</a>&nbsp;

10-signs-of-hyperthyroidism_1_9

Hair loss and brittle nails - Hair and nails grow continuously. This is because a critical thyroid function is sending hormonal signals to trigger hair and nail growth. With hyperthyroidism, additional hormones tell your body to increase the growth of hair follicles and nails in a shorter time.

10-signs-of-hyperthyroidism_1_10

Although it seems that rapid nail growth would be a positive side effect of thyroid dysfunction, this is not the case. This forced growth is happening too quickly. As a result, your body needs to use its natural resources, which can lead to thinner and brittle hair and nails.

10-signs-of-hyperthyroidism_1_11

Sensitive skin or discoloration - Thyroid hormones also affect the health of your skin in different ways. For example, with hyperthyroidism, you may have itchy dry spots on the skin. Your face may feel softer and swollen. You may even notice swelling around your fingertips. Other symptoms include darkening of the skin, rashes and reddish spots.

10-signs-of-hyperthyroidism_1_12

Disturbed sleep or insomnia - It is quite possible that you suffer from disturbed sleep in case of excessive levels of thyroid hormones. They make your body more active than usual. For example, hormonal changes can make the nervous system hyperactive. In addition, you may experience nervousness and anxiety due to thyroid problems that also affect sleep.

10-signs-of-hyperthyroidism_1_13

Changes in the menstrual cycle - Since hyperthyroidism determines accelerated metabolism, the menstrual cycle may become shorter or begin at different times.&nbsp;

10-signs-of-hypothyroidism

10 signs of hypothyroidism 

10-signs-of-hypothyroidism_2_0

10-signs-of-hypothyroidism_2_1

Fatigue&nbsp; - First, when you develop hypothyroidism, your body produces fewer thyroid hormones, making it difficult to recover from everyday stress. As a result, you will start to feel tired more often. You may become slower and slower, you may have difficulty concentrating as mental fatigue or brain fog occurs. <a href="https://link.springer.com/article/10.1007/s12325-019-01080-8?error=cookies_not_supported&amp;code=56c36d9c-f416-4176-b335-115f0af3d09f" target="_blank" data-ref="Hypothyroidism in Context: Where We&rsquo;ve Been and Where We&rsquo;re Going - Advances in Therapy" rel="noopener">[ref.</a>&nbsp;3]&nbsp;

10-signs-of-hypothyroidism_2_2

Sensitivity to cold Hormones secreted by your thyroid gland also regulate body temperature. With fewer hormones, your body has difficulty warming up because your metabolism is slower.

10-signs-of-hypothyroidism_2_3

Constipation - While hyperthyroidism speeds up the digestive process, hypothyroidism slows it down. As a result of these delayed processes, constipation often occurs.&nbsp;

10-signs-of-hypothyroidism_2_4

Dry and itchy skin - Just as overproduction of thyroid hormones leads to skin problems, a lack of these hormones also affects skin health. Skin tends to become dry, itchy and scaly, it may even wrinkle or become pale. These symptoms can also be caused by other skin diseases.

10-signs-of-hypothyroidism_2_5

Weight gain - Thyroid problems lead to a significant slowdown in metabolism. As a result, your body begins to burn less energy and therefore stores more fat. You may find it difficult to exercise because of the fatigue that comes with hypothyroidism.

10-signs-of-hypothyroidism_2_6

Muscle weakness - Without the stimulation of thyroid hormones, your muscles begin to lose their strength. They can even atrophy or become permanently relaxed.

10-signs-of-hypothyroidism_2_7

Muscle aches and cramps - Likewise, your muscles can become painful and low in function. In addition, with a slower metabolism, your body uses catabolism to generate energy. Catabolism is a process that breaks down muscles and other tissues, resulting in weakness, soreness, and possibly pain.

10-signs-of-hypothyroidism_2_8

Joint pain and edema - Catabolism also affects the joints, contributing to fatigue, pain, and even inflammation. In rheumatoid arthritis, for example, we are talking about an autoimmune disease in which the body's immune system mistakenly attacks the joints and causes inflammation and pain. <a href="https://linkinghub.elsevier.com/retrieve/pii/S0140673617307031" target="_blank" data-ref="Redirecting" rel="noopener">[ref.</a>&nbsp;4]&nbsp;

10-signs-of-hypothyroidism_2_9

Abundant or irregular menstrual cycle - Unlike hyperthyroidism, hypothyroidism causes the menstrual cycle to become slower and heavier. Cycles can also become less frequent.

10-signs-of-hypothyroidism_2_10

Depression and brain fog - Among other things, with hyperfunction of SHJ, the nervous system slows down because the body can not use energy as efficiently. In combination with the feeling of fatigue, you can feel sluggish, experience mood swings and depression.

Think you may have a thyroid disorder and have any (or several) of the listed symptoms? Ask your doctor to check thyroid hormone levels, especially if you have a family history of Graves' disease, Hashimoto's autoimmune thyroiditis, or another endocrine disorder. These symptoms may be related to other conditions, but if it is found that the cause is impaired thyroid function, measures can be taken in terms of diet, physical activity, filling nutritional deficiencies and taking medications to normalize the condition.

Symptoms of Hyperfunction and Hypofunction - Impaired Thyroid Function

https://sanatio.s3.eu-west-1.amazonaws.com/ac1a8890-cfa2-45a4-b779-209c199e6e48_middle.jpg

Бетина Цветкова

_-1_0

Symptoms-associated-with-low-creatinine-levels

Symptoms associated with low creatinine levels

Symptoms-associated-with-low-creatinine-levels_0_0

Some common symptoms of low creatinine levels include:

Symptoms-associated-with-low-creatinine-levels_0_1

<ul><li style="font-weight: 400;" aria-level="1">Fatigue</li><li style="font-weight: 400;" aria-level="1">Muscle weakness</li><li style="font-weight: 400;" aria-level="1">Unintentional weight loss</li><li style="font-weight: 400;" aria-level="1">Difficulty concentrating</li></ul>

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals

Causes of Low Creatinine Levels and Relevant Healthcare Professionals

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_0

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_1

<ul><li>Hepatitis, cirrhosis, or liver failure can lead to low creatinine levels</li><li>Consult a hepatologist or gastroenterologist for diagnosis and treatment</li></ul>Malnutrition:

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_2

<ul><li>Poor diet and lack of essential nutrients can result in low creatinine levels</li><li>Consult a nutritionist or dietitian for dietary recommendations</li></ul>Muscular Dystrophy:

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_3

<ul><li>A group of genetic diseases causing progressive muscle weakness and loss of muscle mass</li><li>Consult a neurologist for diagnosis and treatment</li></ul>Aging:

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_4

<ul><li>Natural loss of muscle mass and strength due to aging can lead to low creatinine levels</li><li>Consult a geriatrician or primary care physician for age-related health concerns</li></ul>Pregnancy:

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_5

<ul><li>Increased blood volume during pregnancy can dilute creatinine levels</li><li>Consult an obstetrician or gynecologist for prenatal care</li></ul>

Causes-of-Low-Creatinine-Levels-and-Relevant-Healthcare-Professionals_1_6

Side-effects-of-drugs-that-can-cause-low-creatinine-levels

Side effects of drugs that can cause low creatinine levels

Side-effects-of-drugs-that-can-cause-low-creatinine-levels_2_0

<ul><li style="font-weight: 400;" aria-level="1">Statins: cholesterol-lowering drugs</li><li style="font-weight: 400;" aria-level="1">Angiotensin-converting enzyme (ACE) inhibitors: blood pressure medications</li><li style="font-weight: 400;" aria-level="1">Nonsteroidal anti-inflammatory drugs (NSAIDs): pain relievers such as ibuprofen</li></ul>

Herbal-and-natural-remedies-for-low-creatinine-levels:

Herbal and natural remedies for low creatinine levels:

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_0

Echinacea (Echinacea purpurea):

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_1

<ul><li>Supports immune system function</li><li>May help improve liver function</li></ul>Milk Thistle (Silybum marianum):

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_2

<ul><li>Contains silymarin, a powerful antioxidant</li><li>Promotes liver health and regeneration</li></ul>Astragalus (Astragalus membranaceus):

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_3

<ul><li>May increase energy levels and improve muscle strength</li><li>Supports immune system function</li></ul>Ashwagandha (Withania somnifera):

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_4

<ul><li>Adaptogenic herb that helps the body adapt to stress</li><li>May promote muscle growth and strength</li></ul>

Herbal-and-natural-remedies-for-low-creatinine-levels:_3_5

Lifestyle-Changes-to-Improve-Creatinine-Levels

Lifestyle Changes to Improve Creatinine Levels

Lifestyle-Changes-to-Improve-Creatinine-Levels_4_0

<ul><li style="font-weight: 400;" aria-level="1">Consume a balanced diet with adequate protein intake</li><li style="font-weight: 400;" aria-level="1">Engage in regular exercise to maintain muscle mass</li><li style="font-weight: 400;" aria-level="1">Stay hydrated to ensure proper kidney function</li><li style="font-weight: 400;" aria-level="1">Avoid excessive alcohol consumption</li><li style="font-weight: 400;" aria-level="1">Get adequate sleep and manage stress levels</li></ul>

Questions-and-Answers

Questions and Answers 

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:

Below are ten frequently asked questions that are not covered in the article:

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_0

Q: Can dehydration cause low creatinine levels?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_1

A: Dehydration can cause an increase in creatinine levels, not a decrease.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_2

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_3

Q: Is creatinine level related to kidney function?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_4

A: Yes, creatinine levels are used to evaluate kidney function, but low creatinine levels typically do not indicate kidney problems.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_5

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_6

Q: Can high protein intake cause low creatinine levels?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_7

A: High protein intake may result in increased creatinine levels. Low creatinine levels are more likely due to low protein intake or other factors mentioned in the article.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_8

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_9

Q: Are low creatinine levels in urine the same as low creatinine levels in blood?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_10

A: No, low creatinine levels in urine might indicate a kidney problem, while low creatinine levels in blood are more likely related to muscle mass or liver function.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_11

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_12

Q: How often should I check my creatinine levels?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_13

A: Consult your healthcare provider for personalized recommendations. Regular check-ups are advisable, especially if you have any risk factors or are experiencing symptoms.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_14

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_15

Q: Can stress cause low creatinine levels?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_16

A: While stress itself is unlikely to directly cause low creatinine levels, it may contribute to factors that lead to low creatinine levels, such as muscle loss or malnutrition.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_17

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_18

Q: Are low creatinine levels dangerous?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_19

A: Low creatinine levels are not inherently dangerous, but they may be indicative of underlying health issues that need to be addressed.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_20

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_21

Q: Can low creatinine levels cause fatigue?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_22

A: Fatigue can be a symptom of low creatinine levels, as it may be related to the underlying causes, such as liver disease or malnutrition.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_23

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_24

Q: Can I improve my creatinine levels with supplements?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_25

A: Consult your healthcare provider before starting any new supplements. While some supplements may help address underlying causes of low creatinine levels, it is essential to identify the specific cause to ensure appropriate treatment.

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_26

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_27

Q: Are there any foods I should avoid if I have low creatinine levels?

Below-are-ten-frequently-asked-questions-that-are-not-covered-in-the-article:_5_28

A: There are no specific foods that you need to avoid. However, it is essential to consume a balanced diet with adequate protein and nutrients to support overall health and potentially improve creatinine levels.

Low creatinine levels can be caused by various factors, including liver disease, malnutrition, muscular dystrophy, aging, and pregnancy. Certain medications can also contribute to this condition. Herbal and natural treatments, along with lifestyle changes, can help improve creatinine levels and overall health. Consult the appropriate medical professional for diagnosis and treatment.

 Low Creatinine Levels: Causes and Concerns

https://sanatio.s3.eu-west-1.amazonaws.com/982fbd6b-e4aa-4466-99d0-cecc5cd0e5dd_middle.jpg

Екипът на Санацио

Photo by National Cancer Institute on Unsplash

<ul><li style="font-weight: 400;" aria-level="1">Fatigue</li><li style="font-weight: 400;" aria-level="1">Muscle weakness</li><li style="font-weight: 400;" aria-level="1">Difficulty concentrating</li><li style="font-weight: 400;" aria-level="1">Frequent infections</li></ul>

Possible-causes-and-related-diseases

Possible causes and related diseases

Malnutrition

1. Malnutrition

Malnutrition_1_0

<ul><li style="font-weight: 400;" aria-level="2">Lack of proper nutrition can lead to low creatinine levels</li><li style="font-weight: 400;" aria-level="2">Consult a dietitian or nutritionist for guidance on a balanced diet</li></ul>

Liver-disease

2. Liver disease

Liver-disease_1_0

<ul><li style="font-weight: 400;" aria-level="2">Impaired liver function can cause decreased creatinine production</li><li style="font-weight: 400;" aria-level="2">Consult a hepatologist or gastroenterologist for diagnosis and treatment</li></ul>

Diseases-of-muscle-loss

3. Diseases of muscle loss

Diseases-of-muscle-loss_1_0

<ul><li style="font-weight: 400;" aria-level="2">Muscular dystrophy, multiple sclerosis, or other conditions can lead to decreased muscle mass and reduced creatinine production</li><li style="font-weight: 400;" aria-level="2">Consult a neurologist or physiatrist for appropriate care</li></ul>

Pregnancy

4. Pregnancy

Pregnancy_1_0

<ul><li style="font-weight: 400;" aria-level="2">Creatinine levels may decrease due to increased blood volume and kidney filtration during pregnancy</li><li style="font-weight: 400;" aria-level="2">Consult an obstetrician or primary care physician for routine prenatal care</li></ul>

Pregnancy_1_1

Side-effects-of-medical-drugs-that-can-cause-low-creatinine-levels

Side effects of medical drugs that can cause low creatinine levels

Side-effects-of-medical-drugs-that-can-cause-low-creatinine-levels_2_0

<ul><li style="font-weight: 400;" aria-level="1">Corticosteroids</li><li style="font-weight: 400;" aria-level="1">Chemotherapy drugs</li><li style="font-weight: 400;" aria-level="1">Non-steroidal anti-inflammatory drugs (NSAIDs)</li></ul>

Herbal-and-Natural-Treatments-for-Low-Creatinine-Levels

Herbal and Natural Treatments for Low Creatinine Levels

Astragalus-(Astragalus-membranaceus)

1. Astragalus (Astragalus membranaceus)

Astragalus-(Astragalus-membranaceus)_3_0

<ul><li style="font-weight: 400;" aria-level="2">May improve kidney function and overall immunity</li><li style="font-weight: 400;" aria-level="2">Supports liver health and may help combat fatigue</li></ul>

Rhodiola-(Rhodiola-rosea)

2. Rhodiola (Rhodiola rosea)

Low creatinine levels can be caused by various factors, such as malnutrition, liver disease, muscle wasting diseases, and pregnancy. Recognizing the symptoms and understanding the potential causes will help you address the issue effectively. Consult a medical professional for proper diagnosis and treatment, and consider natural treatments and lifestyle changes to improve your overall health.