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Study finds link between plastic and baby brain development disorders


organs and systems

pregnancy, childbirth, children

Phthalates in some plastics, packaging and toys pose a danger to the brain development of babies and children.

Plastic is a constant companion in our lives - both a helpful friend and a mortal enemy. You will find it very difficult to live plastic-free in the modern world, even if you really want it. It is everywhere, even in our food, where it gets through plastic containers, utensils and packaging, not to mention the microplastic, which seems to be already found in every part of the world and every organism.

In April 2021, a group of scientists called for one of the commonly used ingredients of plastic products - phthalates (and especially ortho-phthalates) to be banned [ref.1].

Phthalates are used to make plastic more flexible and hard to break. But there is alarming evidence that they have a significant negative impact on the nervous development of babies even as early as when the baby is still in the mother's womb. Later, the child is again surrounded by phthalates - in plastic toys, furniture, even packaged food and utensils.

Where are phthalates hiding

Phthalates are found in almost everything: food packaging, clothing, detergents, furniture, vinyl flooring, lubricants and adhesives, bath curtains, plastic car parts, rain and stainresistant products. Unfortunately, they are also found in cosmetics, including shampoo, soap, hairspray and nail polish.

Phthalates have the property of making fragrances durable, which is a desirable quality of cosmetic and detergents. Therefore, on the label they can be hidden simply under the name "fragrance".

Due to the widespread application of phthalates in cosmetics, women are subjected to much greater exposure to them, and given the role of a woman in carrying and breastfeeding the baby, as well as the passage of phthalates from the maternal organism into the fetus, the situation is very alarming.

Packaging of certain food products are among the main sources of di-2-ethylhexyl phthalate (DEHP), as an example of foods that may be contaminated with it are dairy and fatty products and takeaway food.

Phthalates can even be found in children's toys, in building materials and furniture, in PVC pipes, garden hoses - everywhere.

It is therefore extremely difficult to avoid them ourselves and regulatory intervention is needed to prohibit their use.

Phthalates can negatively affect children's brain development

More than 30 studies on the impact of phthalates on the development of the baby in the womb have been conducted until 2019. In this year's report and a call to ban phthalates, scientists found the strongest links between phthalate exposure and:

  • Hyperactivity,
  • Aggression
  • Disobedience,
  • Emotional reactivity,
  • Criminal behaviour,
  • Hyperactivity and attention deficit disorder (ADHD).   

The risk seems to be especially high during the intrautere development of the fetus. To assess the rate of fetal phthalate exposure, the scientists examined its levels in the mother's urine. According to one study, the risk of ADHD in children whose mothers had the highest levels of phthalates in the urine in the second trimester was three times higher than the rest.

It is not entirely clear exactly at what point in development exposure to phthalates is most dangerous, which requires protection all the time.

Phthalates for which harmful effects on the baby's nervous system have been found are:

  • di-2-ethylhexyl phthalate (DEHP),
  • dibutyl phthalates (DBPs),
  • diethyl phthalate (DEP),
  • butylbenzyl phthalate (BBzP).

A systematic review of human studies concludes that prenatal exposure (before birth) of DEHP, DBPs, DEP and BBzP adversely affects cognitive and psychomotor development, internalization and extermination of behavior, attention problems, gender-related game behavior, social response and visual-spatial abilities of children. [ref.2]

Not only phthalates are problematic, but also their metabolites, that is, the substances that form in our body when they are broken down.

Other damage that phthalates do

Various studies link phthalates to childhood obesity, asthma, cardiovascular problems, cancer and reproductive problems, for example, cryptohorism, that is, testicles that do not descend from the abdominal cavity in boys and low sperm count and testosterone levels in men.

  1. Where are phthalates hiding
  2. Phthalates can negatively affect children's brain development
  3. Other damage that phthalates do


  1. Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children, 2021, American Journal of Public Health
  2. The association between prenatal exposure to phthalates and cognition and neurobehavior of children - evidence from birth cohorts, 2019, Neurotoxicology

The author

👩 🔬 Rositsa Tashkova-Kacharova has a Bachelor degree in Molecular Biology and a Master's degree in Microbiology and Microbiological Control. She completed her Master's thesis at the University of Nantes, France. At that time she painted a Christmas tree of bacteria and inspired the announcement of the first competition for drawing with microorganisms Agar Art. For 3 years she was the editor of the journal Bulgarian Science and continues to write about science and medicine.


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